Mixed Results on Vitamin D's Benefit for Aging Hearts

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Some studies have not found a benefit of vitamin D for major cardiovascular events, but the results of the new D-Health Trial suggest that it might be beneficial.

While not whole-heartedly endorsing D supplementation, Neale said older adults might give it some thought.is unlikely to be harmful," she said.

This new trial found no statistically significant difference between vitamin D and placebo, he said. "The totality of currently available evidence suggests that routine vitamin D supplementation does not provide cardiovascular benefits," Fonarow added. For the study, Neale and her colleagues used data from their D-Health Trial in which they randomly assigned more than 21,000 men and women ages 60 to 84 to receive 60,000 IU of vitamin D or a placebo for five years.

During that time, more than 1,300 participants had a major cardiovascular event, including 7% getting the placebo and 6% receiving vitamin D. The rate of major cardiovascular events was 9% lower among those taking vitamin D, compared with those taking the placebo -- about 6 fewer events per 1,000 participants, the researchers found.

 

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