“If it is missing we can say that these patients will be more likely to respond to “immune checkpoint inhibitors” treatment,” he added.Men have XY as sex chromosomes, and women have XX. So when the researchers say
The study authors realized that the Y chromosome regulates the expression of specific genes in many body cells, including those which make up the bladder. Surprisingly, cancer was found to be growing at a faster rate in mice whose tumor cells lacked the Y chromosome. “These results imply that when cells lose the Y chromosome, they exhaust T-cells. And without T-cells to fight cancer, the tumor grows aggressively,” said Theodorescu.The main limitation of the current study is that it has shown the connection only about. There is a great possibility that Y chromosome loss is also linked to other cancer types.