is having a moment, with the dietary supplement receiving lots of attention as a purported weight-loss aid.claiming it can help reduce appetite and improve blood sugar levels.
“Ozempic is a diabetes drug. It also does significantly suppress appetite, and people get significant weight loss taking Ozempic. For those who need it, it works. … With berberine, we can’t be as clear about any of those things.” There is very little evidence supporting any of the claims about berberine, adds Dr. Christopher McGowan, an obesity medicine specialist in Cary, North Carolina.The Council for Responsible Nutrition, a trade group that represents dietary supplement manufacturers, says promising metabolic benefits of berberine have been explored in recent years.
“It’s not because there was some overwhelming clinical trial that said, ‘Wow, berberine — this is your new weight-loss drug.’ It’s because of the right people who had a good anecdotal response to it got the right amount of attention.” It found that "although may affect weight, it does not have a statistically significant and considerable effect" on body mass index, resulting in about a quarter point reduction in BMI.“For people who have a mild weight issue, it might curb appetite enough and help to regulate blood sugar enough that it gives them a little bit of an edge while they’re dieting,” Monti says.
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