There are a number of common health disorders that may actually be a warning sign of dementia, according to an Alzheimer's expert.
With this in mind, Dr Nicole Purcell, a practising neurologist and senior director of clinical care at the Alzheimer's Association, revealed the illness that can interfere with a dementia diagnosis, reports the Mirror. "That gets treated and often the memory issues disappear or improve. Things like medication patients are on. So there are different things that cause dementia-like symptoms."
Treatment has come on leaps and bounds in the last 20 years allowing sufferers to manage symptoms better. For example, there are new pills that can slow down cognitive decline in dementia patients but them being widely accessible is still some way off.
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Evoked mid-frontal activity predicts cognitive dysfunction in Parkinson’s diseaseBackground Cognitive dysfunction is a major feature of Parkinson’s disease (PD), but the pathophysiology remains unknown. One potential mechanism is abnormal low-frequency cortical rhythms which engage cognitive functions and are deficient in PD. We tested the hypothesis that mid-frontal delta/theta rhythms predict cognitive dysfunction in PD. Method We recruited 100 patients with PD and 49 demographically similar control participants who completed a series of cognitive control tasks, including the Simon, oddball and interval-timing tasks. We focused on cue-evoked delta (1–4 Hz) and theta (4–7 Hz) rhythms from a single mid-frontal EEG electrode (cranial vertex (Cz)) in patients with PD who were either cognitively normal, with mild-cognitive impairments (Parkinson’s disease with mild-cognitive impairment) or had dementia (Parkinson’s disease dementia). Results We found that PD-related cognitive dysfunction was associated with increased response latencies and decreased mid-frontal delta power across all tasks. Within patients with PD, the first principal component of evoked electroencephalography features from a single electrode (Cz) strongly correlated with clinical metrics such as the Montreal Cognitive Assessment score (r=0.34) and with National Institutes of Health Toolbox Executive Function score (r=0.46). Conclusions These data demonstrate that cue-evoked mid-frontal delta/theta rhythms directly relate to cognition in PD. Our results provide insight into the nature of low-frequency frontal rhythms and suggest that PD-related cognitive dysfunction results from decreased delta/theta activity. These findings could facilitate the development of new biomarkers and targeted therapies for cognitive symptoms of PD. Data are available upon reasonable request. All data and code are available at narayanan.lab.uiowa.edu and at OpenNeuro: ; ;
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Association of gout with brain reserve and vulnerability to neurodegenerative disease - Nature CommunicationsThe potential association between neurodegenerative disease risk and gout is not fully understood. Here the authors showed that gout is causally related to several measures of brain structure which may explain their higher vulnerability to dementia.
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Health experts share STI warning signs as UK cases reach record highIt's vital to be aware of the symptoms and get yourself checked out as soon as possible for the best chance of treating an STI.
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