The tumor immune microenvironment of nasopharyngeal carcinoma after gemcitabine plus cisplatin treatment - Nature Medicine

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In patients with nasopharyngeal carcinoma, gemcitabine plus cisplatin chemotherapy activates a unique population of innate-like Bcells, which enhance cytotoxic CD8+ Tcells and are associated with better clinical outcomes TumorImmunology

This work was supported by grants from the National Natural Science Foundation of China , the National Postdoctoral Program for Innovative Talents , the Overseas Expertise Introduction Project for Discipline Innovation, 111 Project , the Fundamental Research Funds for the Central Universities , the Natural Science Foundation of Guangdong Province , and the National Key R&D Program of China .

Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Department of Radiation Oncology, Sun Yat-sen University Cancer Center, Guangzhou, China Jiawei Lv, Yuan Wei, Yu-Pei Chen, Guan-Qun Zhou, Xiao-Yu Liang, Yuan Zhang, Shi-Wei He, Qing-Mei He, Jia-Yi Shen, Jun-Yan Li, Wen-Fei Li, Ling-Long Tang, Yan-Ping Mao, Rui Guo, Rui Sun, Na Liu, Dong-Ming Kuang, Ying Sun & Jun Ma

MOE Key Laboratory of Gene Function and Regulation, School of Life Sciences, Sun Yat-sen University, Guangzhou, ChinaJian-Hua Yin, Chen Wei, Cui-Juan Zhang, Zhuo-Li Huang, Yu-Hui Zheng, Wen-Wen Zhou, Ke-Xu Xiong, Si-Qi Wang, Xin Jin & Gui-Bo LiChen Wei, Zhuo-Li Huang & Yu-Hui Zheng CAS Key Laboratory of Regenerative Biology, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, ChinaDepartment of Respiratory Medicine, Guangzhou Institute of Pediatrics, Guangzhou Women and Children’s Medical Centre, State Key Laboratory of Respiratory Diseases, Guangzhou Medical University, Guangzhou, China

 

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