was associated with a 6% increase in mortality.to improve the health of the population in general and, in particular, to reduce the incidence of severe acute respiratory infections," concludes Otavio Ranzani, ISGlobal researcher and first author of the study.There are several biological mechanisms that may explain why long-term exposure to air pollution increases the risk of severe COVID-19.
Another hypothesis is that air pollution may facilitate the infection, as there is published evidence that exposure to fine particulate matter increases the expression of the receptors to which the SARS-CoV-2 virus binds, particularly in the lung. Nonetheless, the study authors believe that more research is needed to gain a better understanding of the main biological pathways involved.The COVAIR-CAT cohort is based on data from the Catalan public health system covering, emergency care and the discharge from hospital of patients with acute conditions. It also includes data from a SARS-CoV-2 surveillance system , which gathered information on PCR and rapid antigen test results in cohort participants in Catalonia.
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