The new technology could revolutionise the field and put an end to animal testing once and for all.
Organ-on-a-chip technology involves growing tiny replicas of human organs on microchips, allowing researchers to test the safety and efficacy of drugs and treatments for animal testing., to override the Federal Food, Drug, and Cosmetics Act of 1938, which mandated animal testing for every new drug development protocol.
For 84 years, US law required preclinical animal testing for new drugs before they were tested on humans. The requirement came into effect after a bad batch ofand a deadly antibiotic medicine caused multiple fatalities in the early 20th century. Don Ingber, the founding director of Harvard University's Wyss Institute for Biologically Inspired Engineering and co-founder of organ-on-a-chip company Emulate, has expressed his belief that animal models used in drug development are “terrible”.
A major advantage of organ-on-a-chip technology is its potential to reduce the number of animals used in medical research., over 20 million animals are used in experiments in the United States each year. This number could be significantly reduced with the use of organ-on-chip technology, as researchers would be able to conduct experiments in a more ethical and accurate manner.of a method to transform adult mouse cells into pluripotent cells that can differentiate into various cell types.
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Source: NatureMedicine - 🏆 451. / 53 Read more »