What’s behind shortages of Adderall, Ozempic and other meds?

In recent months, unexpected demand spikes, manufacturing problems and tight ingredient supplies have contributed to shortages that stress patients, parents and doctors. For some drugs, such as stimulants that treat ADHD, several factors fueled a shortage and make it hard to predict when it will end.Shortages, particularly of generic drugs, have been a longstanding problem.

That situation seems to be improving, said University of Utah Health researcher Erin Fox. But several extended-release doses of the medication, its most popular form, remain in short supply. Injectable drugs used in hospitals and clinics, such as IV saline and some cancer treatments, are more than twice as likely as tablets or topical treatments to experience a shortage, according to a recent report written by Sen. Gary Peters, D-Mich., chairman of the Senate Committee on Homeland Security and Governmental Affairs.The Adderall manufacturing problem hit as more people started taking the drug.

“They’ve been having a run on Ozempic because people don’t want to spend that much on Wegovy,” Schondelmeyer said. “Once a shortage starts with something you make just in time anyway, it’s really hard to resolve it unless all the suppliers are back,” she said.Shortages might lead to treatment delays, which can hurt patients dealing with time-sensitive conditions like cancer.

“You can estimate you’re going to increase your production by 10%,” said Mike Ganio, senior director of pharmacy practice and quality with the American Society of Health-System Pharmacists, “but is that going to be enough?”Meanwhile, conditions that could feed future shortages still exist. The Senate report cited an overreliance on foreign sources as a concern.

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