Association between metabolic syndrome components and gingival bleeding is women-specific: a nested cross-sectional study - Journal of Translational Medicine

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A study published in the Journal of Translational Medicine finds that metabolic syndrome components are associated with gingival bleeding specifically in women. Further research is needed to validate and expand the findings.

]. Also, there is a knowledge gap as to how triglycerides and HDL-cholesterol relate with a condition with systemic implications as periodontitis in a sex-specific manner. Of note, the threshold value of single factors, like serum glucose and arterial BP, for the diagnosis of MetS is lower than what is required to define the corresponding pathologic condition, namely diabetes and hypertension.

The present study aimed to answer the clinical question whether adult individuals who were comparable in terms of potentially confounding factors exposed to at least one MetS component were more likely to suffer from bleeding/non-bleeding periodontal diseases than individuals not exposed to the same factors , and whether the relation exhibited any sexual dimorphism.

Participants were not eligible to periodontal evaluation if at least one of the following exclusion criteria was present: < 5 natural teeth, history of congenital heart disease, valvular heart disease, pacemaker or other artificial cardiac devices, bacterial endocarditis, rheumatic fever, kidney disease requiring dialysis, hemophilia, joint replacements, or malignancy; ongoing pregnancy and breastfeeding.

The extent of BoP was calculated as no. of bleeding sites/no. of probed sites .

In this study, only individuals aged 30 years and above were included, for consistency with previous literature [

 

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