The evolution of non-small cell lung cancer metastases in TRACERx - Nature

The TRACERx study is sponsored by University College London and has been approved by an independent Research Ethics Committee . TRACERx is funded by Cancer Research UK and is coordinated through the Cancer Research UK and UCL Cancer Trials Centre, which has a core grant from CRUK .

Cancer Genome Evolution Research Group, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK Immune Regulation and Tumour Immunotherapy Group, Cancer Immunology Unit, Research Department of Haematology, University College London Cancer Institute, London, UKKarl S. Peggs

Caroline Dive, Alexandra Clipson, Jonathan Tugwood, Alastair Kerr, Dominic G. Rothwell & Elaine KilgourCaroline Dive, Philip Crosbie, Anshuman Chaturvedi, Lynsey Priest, Pedro Oliveira, Alexandra Clipson, Jonathan Tugwood, Alastair Kerr, Dominic G. Rothwell & Elaine KilgourAllan Hackshaw, Abigail Sharp, Sean Smith, Nicole Gower, Harjot Kaur Dhanda, Kitty Chan, Camilla Pilotti & Rachel LeslieNicolai J. Birkbak, Judit Kisistok & Mateo SokacNicolai J.

Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association , Berlin, GermanyZoltan Szallasi & Miklos DiossyZoltan Szallasi & Miklos DiossyDepartment of Physics of Complex Systems, ELTE Eötvös Loránd University, Budapest, HungaryIntegrative Cancer Genomics Laboratory, Department of Oncology, KU Leuven, Leuven, BelgiumThe Francis Crick Institute, London,...

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Evolutionary characterization of lung adenocarcinoma morphology in TRACERx - Nature MedicineAnalyses of the TRACERx study unveil the relationship between tissue morphology, the underlying evolutionary genomic landscape, and clinical and anatomical relapse risk of lung adenocarcinomas MariamJHanjani AACR23 LungCancer
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Body composition and lung cancer-associated cachexia in TRACERx - Nature MedicineResults of the TRACERx study shed new light into the association between body composition and body weight with survival in individuals with non-small cell lung cancer, and delineate potential biological processes and mediators contributing to the development of cancer-associated cachexia.
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The evolution of lung cancer and impact of subclonal selection in TRACERx - NatureAnalyses of multiregional tumour samples from 421 patients with non-small cell lung cancer prospectively enrolled to the TRACERx study reveal determinants of tumour evolution and relationships between intratumour heterogeneity and clinical outcome.
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