Ghana has approved a new malaria vaccine from Oxford University, becoming the first country in the world to take that step forward in fighting the life-threatening disease.
The effort is one of several focused on addressing the disease that kills over 600,000 each year, most of which are children. The complicated structure and lifecycle of the malaria parasite have long stymied efforts to develop vaccines.The R21/Matrix-M vaccine is the second to ever be approved by the WHO and the first to exceed the WHO threshold of 75 per cent efficacy over 12 months of follow-up.
The first-ever malaria vaccine, RTS,S or mosquirix, from British drugmaker GSK, was approved by the WHO in 2021 after decades of work. But a lack of funding and commercial potential thwarted the company’s capacity to produce as many doses as were needed. At the time mosquirix vaccine was approved, the WHO said it was based on results from an ongoing pilot programme in Ghana, Kenya and Malawi that has reached more than 800,000 children since 2019.
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