Post-COVID dyspnea: prevalence, predictors, and outcomes in a longitudinal, prospective cohort - BMC Pulmonary Medicine

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A study published in BMCPulmMed reports that dyspnea (shortness of breath) following hospitalization for COVID-19 is common, persistent, and negatively impacts quality of life. LongCovid

). However, patients with dyspnea had a lower percent-predicted 6-min walk distance compared to patients without dyspnea. There was no significant difference in the troponin or B-type natriuretic peptide levels of patients with and without dyspnea at 12 months post-COVID-19 infection.Patient-reported, respiratory, and cardiac outcomes 12 months post-COVID-19 stratified by presence and absence of dyspnea.

Table 2 Associations of 12-month dyspnea score with 3-month patient-reported, respiratory, and cardiac outcomesThis prospective cohort shows that dyspnea is a frequent symptom following COVID-19, and that most patients with dyspnea do not experience a meaningful improvement in the severity of their symptoms in the first year following infection.

Mood may play a role in post-COVID dyspnea and can predict which patients are at risk for significant persistent dyspnea at 12 months. However, it is unclear whether dyspnea itself is driving these mood abnormalities, or whether the mood abnormality is instead contributing to the development of dyspnea.

 

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Bayesian network modelling to identify on-ramps to childhood obesity - BMC MedicineBackground When tackling complex public health challenges such as childhood obesity, interventions focused on immediate causes, such as poor diet and physical inactivity, have had limited success, largely because upstream root causes remain unresolved. A priority is to develop new modelling frameworks to infer the causal structure of complex chronic disease networks, allowing disease “on-ramps” to be identified and targeted. Methods The system surrounding childhood obesity was modelled as a Bayesian network, using data from The Longitudinal Study of Australian Children. The existence and directions of the dependencies between factors represent possible causal pathways for childhood obesity and were encoded in directed acyclic graphs (DAGs). The posterior distribution of the DAGs was estimated using the Partition Markov chain Monte Carlo. Results We have implemented structure learning for each dataset at a single time point. For each wave and cohort, socio-economic status was central to the DAGs, implying that socio-economic status drives the system regarding childhood obesity. Furthermore, the causal pathway socio-economic status and/or parental high school levels → parental body mass index (BMI) → child’s BMI existed in over 99.99% of posterior DAG samples across all waves and cohorts. For children under the age of 8 years, the most influential proximate causal factors explaining child BMI were birth weight and parents’ BMI. After age 8 years, free time activity became an important driver of obesity, while the upstream factors influencing free time activity for boys compared with girls were different. Conclusions Childhood obesity is largely a function of socio-economic status, which is manifest through numerous downstream factors. Parental high school levels entangle with socio-economic status, and hence, are on-ramp to childhood obesity. The strong and independent causal relationship between birth weight and childhood BMI suggests a biological link. Our study imp BMCMedicine I disagree. If the world adopted the Korean diet (Subway & Pizza Hut commercials on Kdramas I'm looking at you) the obesity rate across all classes would be dramatically reduced. Primal cultures WAY healthier before exposed to SAD (Standard American Diet.) This goes for 🇦🇺as well
Source: medical_xpress - 🏆 101. / 51 Read more »

Misleading claims about ginger and cancer - Full FactA social media post claims that ginger kills 91% of leukaemia cells and shrinks tumours. But this comes from a study about a substance in ginger, not ginger itself. Nor did it always kill that many cells. Nor did it actually shrink tumours. The only thing I've ever seen that works in the natural department is nutrition therapy and coffee enemas. These methods were featured in 'The Food Cure' on Netflix.
Source: FullFact - 🏆 88. / 53 Read more »