Nature Medicine - Erythritol and cardiovascular disease

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⚡Our March issue is live! ⚡ Including data on neoadjuvant immunotherapy in NSCLC, targeted therapy in glioma, a novel approach to stroke rehabilitation, new insights on sweetener erythritol, multiomics, metaomics, news, opinion and much more...

Using observational data from over 200,000 participants with up to 32 years of follow-up, we compared the strengths of eight healthy dietary patterns for general health. We found that diets that lowered hyperinsulinemia, chronic inflammation and diabetes risk may offer the greatest protection against chronic diseases.We describe a 53-year-old man with HIV-1 who received allogeneic CCR5Δ32/Δ32 hematopoietic stem cell transplantation in 2013 to treat acute myeloid leukemia.

To meet a current unmet medical need, we generated 15 genetically engineered mouse models that accurately reflect the key pathogenetic aspects of human multiple myeloma. By coupling mechanistic investigations and pre-clinical immunotherapy testing, these pre-clinical platforms provide knowledge that will aid the optimization of future immunotherapy clinical trial design.

 

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