, compared to around 1% for those who did not. The findings remained after adjusting for socioeconomic factors and smoking status.
The findings challenge the misconception that adult deaths from respiratory diseases are determined only by behavior in adulthood, such as smoking. The researchers say that this highlights the need to prevent childhood respiratory infection and improve the health of children, through targeted public health measures and health service interventions, such as vaccination, improving living conditions, and better diagnosis and treatment of underlying health conditions.
"To prevent the perpetuation of existing adult health inequalities, we need to optimize childhood health, not least by tackling childhood poverty. Evidence suggesting the early life origins of adult chronic diseases also helps challenge the stigma that all deaths from diseases such as COPD are related to lifestyle factors."
Professor Nish Chaturvedi, co-author for the study and PI of NSHD, from University College London, said,"This study highlights the importance of whole of life studies. As the UK's longest running nationally representative cohort study—the MRC NSHD, 1946 British Birth Cohort, is uniquely placed to investigate early life factors that can lead to premature mortality from respiratory disease in later life.
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