This study is the first to evaluate the separate mechanisms of caffeine and non-caffeine components in mitigating the severity of NAFLD, a common issue linked to Type 2 Diabetes.by the University of Coimbra, caffeine, polyphenols, and other natural compounds in coffee could play a role in decreasing the severity of non-alcoholic fatty liver disease in overweight individuals with type 2 diabetes .
Study participants with higher coffee intake had healthier livers. Subjects with higher caffeine levels were less likely to have liver fibrosis, while higher levels of non-caffeine coffee components were significantly associated with reduced fatty liver index scores. The study suggests that for overweight T2D patients, a higher intake of coffee is associated with less severe NAFLD1.
Caffeine intake is associated with decreased liver fibrosis in NAFLD and other chronic liver conditions. It has been suggested that other coffee components, including polyphenols, reduce oxidative stress in the liver, in turn reducing the risk of fibrosis as well as improving glucose homeostasis in both healthy and overweight subjects. All these factors may also alleviate the severity of T2D.
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