By Dr. Chinta SidharthanFeb 13 2023Reviewed by Aimee Molineux In a recent study published in JAMA Network Open, researchers explored the association between severe acute respiratory syndrome coronavirus 2 infections and new diagnoses of alcohol use disorder in the two years since the onset of the coronavirus disease 2019 pandemic.
While the COVID-19 pandemic continues with the emergence of new SARS-CoV-2 variants, albeit with reduced severity and mortality rates, the change in the risk of new AUD diagnoses following SARS-CoV-2 infections remains unclear. To provide cohorts of sufficient size for the analysis, both COVID-19 and ORI patients were divided based on the initial infection time into eight individual cohorts, and the period between January 2020 and January 2022 was divided into three-month blocks of time. The COVID-19 cohort was defined by either a positive COVID-19 ribonucleic acid test result or an International Classification of Diseases, Tenth Revision encounter diagnosis code for COVID-19.
Results The results suggested a significant increase in the risk of new AUD diagnoses in the three months following a COVID-19 diagnosis, but the risk decreased to non-significant levels in the next three months. For two weeks to three months after COVID-19 diagnosis, there was a significant increase in the hazard ratio for a new diagnosis of AUD among the COVID-19 cohort compared to the ORI cohort.
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