Acute phase characteristics and long-term complications of pulmonary embolism in COVID-19 compared to non-COVID-19 cohort: a large single-centre study - BMC Pulmonary Medicine

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A study published in BMCPfulmMed reports that pulmonary embolism (PE) in patients with COVID-19 showed significant differences compared to non-COVID patients, and that the usual tools for risk stratification of PE are valid in COVID-19-associated PE.

]. These data suggest that in situ vascular thrombosis instead of distal embolism is this population’s underlying physiological mechanism of PE.

Bearing in mind all these gaps in the current knowledge, the present study aimed to describe the clinical, analytical, and radiological characteristics, the correlation between severity assessment and outcomes of PE during the acute phase, and the long-term complications, including recurrence of VTE and CTEPH in COVID patients, and to compare them with a non-COVID cohort.

The primary outcome in the present study was the combination of in-hospital all-cause mortality and the need for mechanical ventilation. We specifically investigated the causes of death. We analyzed the ability of the risk stratification model for death in PE developed in the general population for predicting mortality in COVID patients. Second, we analyzed the severity of PE according to PE size , the presence of RVD in the transthoracic echocardiography, and the sPESI score.

 

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