Vitamin D Supplements Linked to Decreased Diabetes Risk for Adults With Prediabetes

A recent review published in Annals of Internal Medicine on February 7, 2023, found that higher vitamin D intake was linked to a 15% decrease in the likelihood of developing type 2 diabetes in adults with prediabetes.

Vitamin D supplementation may lower diabetes risk for the more than 10 million adults with prediabetes. A review of clinical trials has found that higher vitamin D intake was associated with a 15 percent decreased likelihood for developing type 2 diabetes in adults with prediabetes. The review was published on February 7, 2023, inVitamin D is a fat-soluble vitamin available in or added to some foods, as a supplement, or produced by the body when ultraviolet rays from sunlight strike the skin. Vitamin D has many functions in the body, including a role insecretion and glucose metabolism.

Researchers from Tufts Medical Center conducted a systematic review and meta-analysis of three clinical trials comparing vitamin D supplement impacts on diabetes risk. The authors found that over a three-year follow-up period, new-onset diabetes occurred in 22.7 percent of adults who received vitamin D and 25 percent of those who received placebo, which is a 15 percent relative reduction in risk.

In an accompanying editorial, authors from University College Dublin and Food Safety Authority of Ireland, highlight that previous data have demonstrated significant adverse effects for high vitamin D intake. They argue that professional societies promoting vitamin D therapy have an obligation to warn physicians about both required vitamin D intake and safe limits. They advise that this very-high-dose vitamin D therapy might prevent type 2 diabetes in some patients but may also cause harm.

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