Off-the-shelf CAR T cells for multiple myeloma - Nature Medicine

Nevertheless, generation of autologous CAR T cell products is extremely time consuming and costly, prompting researchers to explore alternative strategies to overcome these limitations.

In this issue ofreport results of part A of the phase 1 UNIVERSAL clinical trial, which evaluated ALLO-715, an allogeneic off-the-shelf anti-BCMA CAR T cell product. The study demonstrated that administering these off-the-shelf CAR T cells is feasible, and that the therapy has clear anti-malignancy activity in multiple myeloma.

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theNCI Thanks for the pay wall.

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