By Pooja Toshniwal PahariaJan 17 2023Reviewed by Aimee Molineux In a recent review published in Nature Reviews Microbiology, researchers explored existing literature on long coronavirus disease . They highlighted key immunological findings, similarities with other diseases, symptoms, associated pathophysiological mechanisms, and diagnostic and therapeutic options, including coronavirus disease 2019 vaccinations.
Key long COVID findings and similarities with other diseases Studies have reported persistently reduced exhausted T lymphocytes, dendritic cells, cluster of differentiation 4+ lymphocyte and CD8+ lymphocyte counts, and greater PD1 expression. In addition, increase in innate cell immunological activities, non-classical monocytes, expression of interferons -β, λ1, and interleukins -1β, 4,6, tumor necrosis factor .
Long COVID symptoms and underlying pathophysiological mechanisms Antibodies eBook Compilation of the top interviews, articles, and news in the last year. Download a free copy Long COVID-associated organ damage reportedly results from COVID-19-induced inflammation and associated immune responses. Cardiovascular long COVID symptoms such as chest pain and palpitations have been associated with endothelial dysfunction, micro-clotting, and lowered vascular density.
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