By Bhavana KunkalikarDec 15 2022Reviewed by Aimee Molineux In a recent study published in the Asian Journal of Andrology, researchers assessed the influence of coronavirus disease 2019 vaccination on sperm characteristics.
About the study In the present study, researchers examined the differences among sperm parameters before and post-administration of various SARS-CoV-2 vaccinations. Results Related StoriesSeven database-screened studies were evaluated for quality and incorporated into the quantitative analysis.
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Brain fog of post-COVID-19 condition and Chronic Fatigue Syndrome, same medical disorder? - Journal of Translational MedicineBackground Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is characterized by persistent physical and mental fatigue. The post-COVID-19 condition patients refer physical fatigue and cognitive impairment sequelae. Given the similarity between both conditions, could it be the same pathology with a different precipitating factor? Objective To describe the cognitive impairment, neuropsychiatric symptoms, and general symptomatology in both groups, to find out if it is the same pathology. As well as verify if the affectation of smell is related to cognitive deterioration in patients with post-COVID-19 condition. Methods The sample included 42 ME/CFS and 73 post-COVID-19 condition patients. Fatigue, sleep quality, anxiety and depressive symptoms, the frequency and severity of different symptoms, olfactory function and a wide range of cognitive domains were evaluated. Results Both syndromes are characterized by excessive physical fatigue, sleep problems and myalgia. Sustained attention and processing speed were impaired in 83.3% and 52.4% of ME/CFS patients while in post-COVID-19 condition were impaired in 56.2% and 41.4% of patients, respectively. Statistically significant differences were found in sustained attention and visuospatial ability, being the ME/CFS group who presented the worst performance. Physical problems and mood issues were the main variables correlating with cognitive performance in post-COVID-19 patients, while in ME/CFS it was anxiety symptoms and physical fatigue. Conclusions The symptomatology and cognitive patterns were similar in both groups, with greater impairment in ME/CFS. This disease is characterized by greater physical and neuropsychiatric problems compared to post-COVID-19 condition. Likewise, we also propose the relevance of prolonged hyposmia as a possible marker of cognitive deterioration in patients with post-COVID-19.
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Obesity and type 2 diabetes impair mRNA COVID vaccine efficacy in mouse modelObesity and type 2 diabetes impair mRNA COVID vaccine efficacy in mouse model Diabetes Efficacy Obesity Type2Diabetes Vaccine Coronavirus Disease COVID biorxivpreprint BostonChildrens harvardmed UMmedschool DanaFarber broadinstitute
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