, but suggests that any increased risk with current smoking is likely to be small and will need to be clarified as the epidemic progresses and more data accumulate.
We similarly investigated the change in the hypertension hazard ratio adjusted for age and sex, to 0.89 with all covariates included), and found that diabetes and obesity were principally responsible for this reduction adjusted for age, sex, diabetes and obesity).
Our analyses provide a preliminary picture of how key demographic characteristics and a range of comorbidities—which were a priori selected as being of interest in COVID-19—are jointly associated with poor outcomes. These initial results may be used to inform the development of prognostic models. We caution against interpreting our estimates as causal effects.
The study also has some important limitations. In our outcome definition, we included clinically suspected cases of COVID-19, because testing has not always been carried out, especially in older patients in care homes. However, this may have resulted in some patients being incorrectly identified as having COVID-19.
Our large population may not be fully representative. We include only 17% of general practices in London—where many of the earlier cases of COVID-19 occurred—owing to the substantial geographical variation in the choice of electronic health record system. The user interface of electronic health records can affect prescribing of certain medicines
HKUniversity No shit? *puff puff puff puff
HKUniversity
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Brain fog of post-COVID-19 condition and Chronic Fatigue Syndrome, same medical disorder? - Journal of Translational MedicineBackground Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is characterized by persistent physical and mental fatigue. The post-COVID-19 condition patients refer physical fatigue and cognitive impairment sequelae. Given the similarity between both conditions, could it be the same pathology with a different precipitating factor? Objective To describe the cognitive impairment, neuropsychiatric symptoms, and general symptomatology in both groups, to find out if it is the same pathology. As well as verify if the affectation of smell is related to cognitive deterioration in patients with post-COVID-19 condition. Methods The sample included 42 ME/CFS and 73 post-COVID-19 condition patients. Fatigue, sleep quality, anxiety and depressive symptoms, the frequency and severity of different symptoms, olfactory function and a wide range of cognitive domains were evaluated. Results Both syndromes are characterized by excessive physical fatigue, sleep problems and myalgia. Sustained attention and processing speed were impaired in 83.3% and 52.4% of ME/CFS patients while in post-COVID-19 condition were impaired in 56.2% and 41.4% of patients, respectively. Statistically significant differences were found in sustained attention and visuospatial ability, being the ME/CFS group who presented the worst performance. Physical problems and mood issues were the main variables correlating with cognitive performance in post-COVID-19 patients, while in ME/CFS it was anxiety symptoms and physical fatigue. Conclusions The symptomatology and cognitive patterns were similar in both groups, with greater impairment in ME/CFS. This disease is characterized by greater physical and neuropsychiatric problems compared to post-COVID-19 condition. Likewise, we also propose the relevance of prolonged hyposmia as a possible marker of cognitive deterioration in patients with post-COVID-19.
Source: BioMedCentral - 🏆 22. / 71 Read more »
Cancer drug trial using COVID vaccine mRNA technology shows 'highly encouraging' resultsScientists are optimistic that mRNA vaccines will improve survival rates in many cancers that are currently hard to beat. A demonstrably harmful technology that couldn't make it out of animal trials over a 20 year period (without killing said animals) and now clearly harmful to humans in the couldn't be more massive or more conclusively bad Covid 'trial'. Snake oil, anyone? Shouldn’t be allowed, it’s changed the genetics of the human race! That’s a no from me
Source: SkyNews - 🏆 35. / 67 Read more »