idney cancer is one of the 10 most-diagnosed cancers in the United States. Like many of the other cancers on that list—including colon and rectal cancer—kidney cancer is more common now than it used to be. But unlike some others, the underlying causes of kidney cancer are often hard to discern.
While the likelihood that a smoker develops kidney cancer is relatively small, researchers have estimated that smoking increases a person’s risk for the disease by 20-50%. “When you inhale the carcinogens in tobacco, they are absorbed through the lungs into the bloodstream,” explains Dr. Zachary Smith, a kidney cancer specialist at Washington University in St. Louis. It’s the job of the kidneys to clean and filter blood.
While the connection between hypertension and kidney cancer is well-established, experts aren’t sure exactly how high blood pressure contributes to the development of the disease. “We know the association is there, but the exact causality isn’t clear,” Kundu says. One theory is that hypertension may induce a state of chronic inflammation, which may impair kidney health in several ways that could elevate kidney cancer risk.
and blood-oxygen imbalances caused by excess weight could also be factors. It’s possible that these and other weight-related biological changes could ultimately explain the obesity-kidney cancer connection, but more work is needed.Again, only a small percentage of kidney cancers—roughly 3% to 5%—are caused by inherited genetic mutations. So far, researchers have identified at least 12 heritable genes or mutations that can be passed down within families that increase the risk of kidney cancer.
Mikecraft?
As we are used to say in Italy: 'Thanks to the dick'!
and many other cancers too .........
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