CanRisk-Prostate: A Comprehensive, Externally Validated Risk Model for the Prediction of Future Prostate Cancer | Journal of Clinical Oncology

it is likely that the model predictions reflect more clinically significant disease risks. This may also partly explain the underpredicted risks in UK Biobank, before recalibration. However, further research is needed on genetic predictors for aggressive PCa and on validating the prediction of specifically aggressive PCa risks. The model does not incorporate nonfamilial/nongenetic factors, such as PSA or other clinical measurements.

Joe Dennis, Naomi Wilcox, Tokhir Dadaev, Koveela Govindasami, Goska Leslie, Kenneth Muir, Elizabeth Bancroft, Zsofia Kote-Jarai, Rosalind EelesTommy Nyberg, Mark N. Brook, Lorenzo Ficorella, Andrew Lee, Xin Yang, Koveela Govindasami, Michael Lush, Douglas F. Easton, Zsofia Kote-Jarai, Antonis C. Antoniou

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