Stiff-person syndrome , also known as, Moersch-Woltman syndrome, is a rareSPS is an acquired neurological disorder and the cause is unknown.
Those who have "classic SPS" may initially experience aching discomfort, stiffness, or pain, especially in the lower back or legs. In the early stages of the disease, the stiffness may come and go but it will eventually become permanent. These spasms may occur out of nowhere or can be stimulated. For instance, some spasms could be triggered by a loud noise, minor physical contact, cold temperatures, or anything that can trigger a heightened emotional response. These spasms are often painful and usually further exacerbate any muscle stiffness, according to Rarediseases.org.
It can usually be diagnosed through blood tests. It is a rare disease and about less than 5,000 people have been diagnosed with SPS in the United States, the NIH website says. In addition to "classic SPS," there are other variants of this disease that have been reported in patients, according to Rarediseases.org. This variant of SPS is characterized as just one area of the body being impacted by the disease, for example, the legs.
Some symptoms associated with this variant include "vertigo, a lack of coordination of voluntary muscles , and difficulty speaking ,"In some cases, nerves in the brain may become impacted and can lead to paralysis of certain eye muscles, rapid, involuntary eye movements, difficulty swallowing, and hearing loss. This variant is rare and impacts the nervous system of some cancer patients. It is more prevalent in breast and lung cancer patients.
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Source: Nature - 🏆 64. / 68 Read more »