Shorter course of radiation therapy yields comparable results for patients with non-metastatic soft tissue sarcoma

therapy doses per treatment over fewer days relative to conventional therapy. Thirty-one percent of patients developed major wound complications within 120 days of surgery, while local tumor control was 93% at two-year follow-up—both comparable to historically reported rates with the longer treatment course.

A major side effect of pre-operative radiation therapy in patients with non-metastatic STS is an increased risk ofcomplications after surgery. Patients have a heightened risk of needing a second operation for wound repair, extensive wound management and readmission to the hospital. "Research shows that patients receiving their treatment at cancer centers with sarcoma specialists have better survival and functional outcomes. Being able to shorten our patients' treatment time from five to three weeks may improve care accessibility because patients would be able to reduce their time away from home if they do not live near a sarcoma specialty center," Guadagnolo said.

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Source: BioMedCentral - 🏆 22. / 71 Read more »

Patients with cancer, suppressed immune system at high risk for severe COVID if treated with systemic drug therapiesPatients with cancer and a weakened immune system who are treated with immunotherapies tend to fare far worse from COVID-19 than those who haven't received such therapies in the three months before their COVID diagnosis, show findings in a new study by researchers at Dana-Farber Cancer Institute, and across the U.S., Canada and Mexico. Researchers found worse outcomes in both the disease itself as well as the fierce immune response that sometimes accompanies it.
Source: medical_xpress - 🏆 101. / 51 Read more »