What are the effects of pesticides on neonates' health?

By Dr. Liji Thomas, MDSep 20 2022Reviewed by Danielle Ellis, B.Sc. Pesticide use is universal today as part of the agricultural revolution that ushered in an era of bigger, better farming. However, generations after this practice began, scientists warned against these compounds' harmful effects on the soil, water, and air.

The impact of such compounds, called xenobiotics, on newborns, defined as infants within 28 days of life, is the subject of this paper, published in the journal Science of the Total Environment. These include heavy metals and organic compounds like pesticides, plasticizers, drugs, and dyes, among others.

Pesticides are a unique class of chemicals with biocidal properties and distinctive metabolic pathways in the human body. They belong to several structural classes, which indicates that they undergo several different routes of metabolism. Some such organic pesticides include organochlorine and organophosphate pesticides, carbamates, pyrethrins, and pyrethoids.

Related StoriesNeurologic disorders, including cognitive dysfunction, have also been linked to some OP and OC exposure. The results may include inattention, attention deficit and hyperactivity disorder , autism spectrum disorder , and aggressive or depressive behavior in children. Again, blood collection is invasive, while hair and nail clippings can be obtained non-invasively. However, the former is most reliable for measuring the original compounds' concentrations. Whole blood or dried blood spots may be used, the latter being far more convenient to obtain and handle.

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