Concerns over accuracy of COVID rapid test results when first sick

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California officials warn of misleading COVID rapid test results: Sick but 'negative'

The planned changes — CDC leaders call it a ‘reset’ — come amid ongoing criticism of the agency’s response to COVID-19, monkeypox and other public health threats.Because of this, the agency “recommends repeat testing following a negative result, whether or not you have COVID-19 symptoms.”dominant Omicron subvariant, BA.5

Gonzales said he has noticed an additional lag in how long it takes a rapid test to turn positive following the onset of symptoms — especially early on.Health officials recommend that anyone infected with the coronavirus isolate for at least 5 days — but for many, that timeline may be overly optimistic.

“People should use multiple tests over a certain time period, such as two to three days, especially when the people using the tests don’t have COVID-19 symptoms,” the agency said in its statement. “The FDA is highlighting the continued need for repeat, or serial, testing when people get a negative result with an at-home COVID-19 antigen test, including recommending additional testing over a longer period of time.

Another possible reason is that the immune systems of people who have been vaccinated and boosted are more likely to recognize an exposure to the coronavirus quickly, triggering symptoms early as a way to fight off disease but before there are levels of virus in the body high enough for a rapid test to detect.

As a result, in a vaccinated and boosted person, the body can quickly issue its own alarm indicating COVID-19 has arrived, but it can take longer for enough of the virus to be detectable by a rapid test. If you do get a negative PCR test result and are still symptomatic, Ferrer said you should contact your healthcare provider.

 

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