Healthcare Press

Noncoding RNA-mediated molecular bases of chemotherapy resistance in hepatocellular carcinoma - Cancer Cell International

  • 📰 BioMedCentral
  • ⏱ Reading Time:
  • 17 sec. here
  • 2 min. at publisher
  • 📊 Quality Score:
  • News: 10%
  • Publisher: 71%

Health Health Headlines News

Health Health Latest News,Health Health Headlines

A Review published in Cancer Cell International presents a summary of the latest progress in the investigation of noncoding RNA-related chemoresistance in hepatocellular carcinoma.

]. Specifically, circ_0003998 is elevated in doxorubicin-resistant HCC cells and serves as a ceRNA to downregulate miR-218-5p, which is negatively associated with the content of the EMT marker EIF5A2. Consistently, circFoxo3 is overexpressed in HCC samples and promotes adriamycin resistance via the miR-199a-5p/ABCC1 axis, contributing to EMT progression.

For brevity, macroautophagy henceforth referred to as autophagy, involves the formation of autophagosomes in the cytoplasm, fusion with lysosomes or vacuoles and degradation of autolysosomes by proteases or nucleases, which is regulated via autophagic essential genes and signaling pathways to sustain the microenvironment.

 

Thank you for your comment. Your comment will be published after being reviewed.
Please try again later.
We have summarized this news so that you can read it quickly. If you are interested in the news, you can read the full text here. Read more:

 /  🏆 22. in HEALTH

Health Health Latest News, Health Health Headlines

Similar News:You can also read news stories similar to this one that we have collected from other news sources.

Father diagnosed with terminal cancer travels to Turkey for potentially lifesaving operationA man who diagnosed with terminal cancer just two weeks after getting married will today have an operation he hopes can save his life.
Source: ShropshireStar - 🏆 98. / 51 Read more »