Genetically modified pig hearts transplanted into brain-dead humans in US as doctors face organ shortage

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Genetically modified pig hearts have been transplanted into humans in a breakthrough that could pave the way for more trials and tackle an organ shortage facing doctors

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In the past month, researchers at NYU Langone Health in the US transplanted pig hearts into two people who had recently suffered catastrophic heart failure and were left brain dead but remained on life support. In both cases the new hearts had strong beats and were not rejected immediately by the host bodies - functioning well for the duration of the three-day experiment.

"The heart was literally banging away. It was contracting completely normally," surgeon Dr Nader Moazami said.The doctors hope that their research model - of testing pig organs in clinics with deceased patients - can help prepare the medical community for clinical trials and reduce the chances that living patients' immune systems will turn on new organs.

The research is being conducted against a background of organ shortage in the US, with less available for transplant than are needed by patients.

 

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It was done by an Indian doctor 24 years ago but was arrested.

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