We thank all brain donors, patients and their families for the tissue specimens used in this study and members of Ming and Song laboratories for discussion; B. Temsamrit, E. LaNoce and A. Garcia for technical support; A. Angelucci and J. Schnoll for lab coordination; F. H. Gage, G. Kempermann, S. Jessberger and K. M. Christian for comments; O. Spicer, J. Glausier, A. LeFevre, J. Cottrell and J. Hussain for assistance with human tissue acquisition; K. McCanon, Z. Yang, H.
Department of Biomedical and Health Informatics , Children’s Hospital of Philadelphia, Philadelphia, PA, USADepartment of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USAInstitute for Regenerative Medicine, University of Pennsylvania, Philadelphia, PA, USAThe Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USALieber Institute for Brain Development, The Solomon H.
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