Immunotherapy for rectal cancer with certain mutation
Specifically, it focused on a subset of rectal cancer patients whose tumors contained a specific genetic mutation. The researchers said the body’s immune cells contain a safeguard known as a checkpoint to prevent them from attacking normal cells. But cancer cells can impact this safeguard and shut down immune cells, allowing a tumor to hide and grow.
"The immunotherapy shrank the tumors much faster than I expected," Cercek said in the statement. "My research nurse Jenna Sinopoli would tell me, ‘The patient has only received one treatment and already they’re not bleeding anymore and their terrible pain has gone away.’" The second was a desire for patients to avoid the "toxicity" often associated with common cancer treatments.
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