Rat testicle cells make sperm after being frozen for 23 years

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Pre-pubescent boys can be made infertile by cancer treatment, but freezing immature testicle tissue may offer a way to restore their fertility later.

Eoin Whelan, Whelan et al., 2022, PLOS Biology, CC-BY 4.0

The findings suggest that children who have testicle tissue frozen before cancer treatment may be able to have the tissue reimplanted so they can one day have their own biological children through in vitro fertilisation , saysChemotherapy to treat cancer can kill stem cells in the testicles that make sperm.

 

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