UK researchers identify T-cell targets for future COVID vaccines

People begin to receive COVID-19 vaccines in NorthamptonLONDON - British researchers said on Wednesday they had identified proteins in the coronavirus that are recognised by T-cells of people who are exposed to the virus but resist infection, possibly providing a new target for vaccine developers.

They found that, while a subset of the workers did not generate antibodies or test positive with PCR tests, they had still generated a large and broad T-cell response following possible exposure. "What is really informative is that the T-cells detected in these individuals, where the virus failed to establish a successful infection, preferentially target different regions of the virus to those seen after infection."

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