Corticosteroids 'mainstay' for treatment of severe COVID-19 in Singapore; new antibody therapy to be used soon

are the"mainstay" for the treatment of severe COVID-19 in Singapore, while an antibody therapy will also soon be used to treat patients with mild to moderate symptoms.

Corticosteroids are normally used to treat a range of allergic reactions, such as rheumatoid arthritis or asthma. As of noon on Tuesday, 1,512 COVID-19 cases in Singapore were warded in hospital, with 247 cases requiring oxygen supplementation. There were 34 COVID-19 cases in the intensive care unit.Two antibody therapies have been recently granted interim authorisation under the Pandemic Special Access Route by the Health Sciences Authority to treat those with mild to moderate COVID-19.

HSA said clinical data from a Phase 3 study showed that casirivimab-imdevimab demonstrated a 70 per cent reduction in the"relative risk for progression to requiring acute treatment in hospital or death due to COVID-19".

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