Flu Shot Timing: What's Optimal?

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When is the best time to get a flu shot? Experts weigh in:

vaccine in 1943, the study's authors observed that antibodies to influenza declined by about one third within 4 to 5 months after vaccination."for everyone 6 months and older but determining the best time to get vaccinated can be complicated, Ferdinands notes. Current recommendations — which Ferdinands says clinicians should continue to follow — suggest that ideally, vaccination should occur by the end of October.

Patients testing positive for influenza were considered cases, while those testing negative were used as controls. Participants were considered vaccinated if they had documented evidence of at least one dose of influenza vaccine at least 14 days before they became ill. Results were adjusted for factors such as age, race, season, past year hospitalizations, and indicators of underlying health conditions. Vaccine efficacy against influenza-associated hospitalizations declined by an average of 7.5%–8.5% for each 30 days postvaccination, depending on influenza type

Public health benefits could be significant, given the millions who become ill and tens of thousands who die from influenza in the U.S. each year, she says.

 

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