The World Health Organization's plea came as Russia saw its highest daily death toll from the pandemic that has killed at least 4.3 million people worldwide.
A WHO call last month for the investigation's second stage to include audits of the Wuhan labs infuriated Beijing, with vice health minister Zeng Yixin saying the plan showed "disrespect for common sense and arrogance towards science". Analysing and improving lab safety and protocols "including in China, is important for our collective biosafety and security", it said.
In the US, the health department is to require all its public-facing health care workers to get jabs amid a surge in hospitalisations driven by the Delta variant.
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