Bernie Delgado prepares doses of the Pfizer-BioNTech vaccine in a cold storage room set up at Pratt & Whitney Stadium in East Harford, Conn., Feb. 4, 2021.
The vaccines “even the playing field,” Gommerman said, so that anyone who has recovered from COVID-19 produces enough antibodies to protect against the virus. The researchers obtained blood samples from 10 volunteers in the Seattle COVID Cohort Study who were vaccinated months after contracting the coronavirus. Seven of the participants received the Pfizer-BioNTech vaccine, and three received the Moderna vaccine.
In that study, most people had been infected with the coronavirus eight or nine months earlier but saw their antibodies increase by a hundredfold to a thousandfold when given the first dose of a vaccine. After the second dose, however, the antibody levels did not increase any further. Krammer led another of the new studies, which showed that people who have had COVID-19 and received one dose of a vaccine experienced more severe side effects from the inoculation and had more antibodies compared with those who had not been infected before.
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