, which are associated with extremely disobedient and hostile behavior, including property destruction, theft, and cruelty toward animals in the case of patients with severe CD. This new study suggests that individuals with ADHD plus ODD and/or CD appear to possess a unique genetic segment that may be detected early in life to unlock proactive, rather than reactive, treatments, researchers say.
Researchers used data on roughly 4,000 individuals affected by ADHD and DBDs drawn from the European project Agressotype, which explored the neurobiological basis of. Genome-wide association studies were used to analyze the genetic contribution of changes in a single DNA nucleotide to these psychiatric disorders.
Researchers discovered a genomic segment in the chromosome 11 that increased the risk of comorbid ADHD and DBDs, suggesting that genetics are more determining in those with boththan in those with only ADHD.