GSK to widen COVID-19 antibody treatment trial after safety clearance

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GlaxoSmithKline and partner Vir Biotechnology will expand their trial of an experimental antibody to treat COVID-19 after initial use by a group of volunteers did not raise any safety concerns.

The two partners in August started testing the antibody on early-stage COVID-19 patients, hoping to keep symptoms from progressing.After testing the drug on 20 U.S. participants for safety, the trial will now expand as planned to 1,300 patients globally.Interim trial results may be available as early as the end of 2020. Complete efficacy results are expected as early as January or later in the first quarter of 2021.

An experimental two-antibody combination under development by Regeneron was mong the drugs used on U.S. President Donald Trump for his COVID-19 infection. Eli Lilly, which will get manufacturing help from Amgen, last month also released data showing that one of its antibodies lowered patient virus levels and could prevent disease progression.

 

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