, calling for the administration of steroids to all patients in the “severe and critical” category, based on findings that the treatment could reduce mortality by slightly more than one third.
The new conclusions were reached through a meta-analysis of seven different studies, each exploring the efficacy of corticosteroids in the most serious cases of COVID-19. The combined sample group from all seven studies included 1,703 severely ill patients, 678 of whom were administered steroids and 1,025 who received ordinary care or a placebo. All of the patients were hospitalized and most were on ventilators.
“The consistent findings of benefit in these studies provide definitive data that corticosteroids should be first-line treatment for critically ill patients with COVID-19,” wrote Dr. Hallie Prescott, professor of medicine at the University of Michigan, and Dr. Todd Rice, professor of Medicine at Vanderbilt University, in
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