In addition, the researchers also found that there was some evidence to suggest that high alcohol intake was also linked with coronary artery disease, atrial fibrillation and aortic aneurysm.
The team points out that the findings are in line with previous studies, which have also shown that heavy drinking is linked with an increased risk of certain cardiovascular diseases. However, as these were observational studies, they could not determine a cause and effect relationship. “Since genetic variants are determined at conception and cannot be affected by subsequent environmental factors, this technique allows us to better determine whether a risk factor — in this case, heavy alcohol consumption — is the cause of a disease, or if it is simply associated,” said senior researcher Susanna Larsson, Ph.D. “To our knowledge, this is the first Mendelian randomization study on alcohol consumption and several cardiovascular diseases.
“Higher alcohol consumption is a known cause of death and disability, yet it was previously unclear if alcohol consumption is also a cause of cardiovascular disease. Considering that many people consume alcohol regularly, it is important to disentangle any risks or benefits,” Larsson said. The American Heart Association advises alcohol in moderation as part of a healthy diet, which they say is no more than one alcoholic drink per day for women and two alcoholic drinks per day for men. These recommendations also apply to non-pregnant women and in cases where there is no risk to any existing health conditions, medication-alcohol interaction or personal safety and work situations. One drink is equivalent to 12 ounces of beer ; 5 ounces of wine ; or 1.
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