Doctor gambles on clot-busting drug to save virus patients

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With no vaccine or approved treatment for the coronavirus, many overwhelmed doctors are following trails of clues to figure out what to try next, such as using medication aimed at breaking up blood clots on severely ill patients, an experimental treatment that has helped a few at death's door.

In this Monday, March 30, 2020 photo provided by Mount Sinai, from left, Drew Copeland, RPSGT; Dr. Thomas Tolbert, Dr. Brian Mayrsohn, and Dr. Hooman Poor, stand with a ventilator prototype they developed from a sleep apnea machine at Mount Sinai hospital in New York. WASHINGTON -- The woman was dying. New York's Mount Sinai Hospital was about to call her husband and break the news that there was nothing left to try. Then Dr. Hooman Poor took a gamble.

Already, many hospitals are attempting preventive doses of blood thinners to keep clots from forming. There's huge debate over what kind to try, what dose is safe -- the drugs can cause dangerous bleeding -- and how soon to start. Twenty minutes after the injection of tPA, her oxygen levels rose. Poor was elated. But not for long.

But last weekend, Poor's team tested the new clot-fighting approach in four additional severely ill patients. One didn't survive, dying of cardiac arrest from a massive blood clot in his heart. Pugliese called Poor's tPA report "very intriguing" and concluded: "What these doctors did in these very ill patients who were dying was a judgment call, and it was the right thing to do."

 

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Are they gambling on the chloroquine cocktail? Or do they pass because Orange Man Bad?

Surprising how CTV will discuss a drug which failed but won't discuss a drug which works 91% of the time?

It’s a time for gambling ... good for him

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