Early detection and treatment of rheumatoid arthritis results in lower treatment-related costs over 5 years compared with later diagnosis.The study enrolled 431 patients in the Leiden Early Arthritis Clinic at the Leiden University Medical Center, Leiden, Netherlands.Early treatment was defined as a symptom duration of under 12 weeks, and later treatment defined as symptom duration over 12 weeks.
Prescription data from patient records and 2022 disease-modifying antirheumatic drug prices was used to determine overall costs over 5 years. Autoantibody-negative and autoantibody-positive RA were studied separately due to possible differences in disease severity.For the 165 patients with autoantibody-negative RA, late treatment was associated with 316% higher costs over 5 years than early treatment In the 43 patients with antibody-positive RA only prescribed biologics, costs were 46% higher for those with delayed treatment.
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