PFAS exposure in early life: Health risks and maternal-fetal transport mechanisms

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Chemicals News

Breast Milk,Children,Placenta

Polyfluoroalkyl substances (PFAS) are a class of chemicals extensively used in consumer goods production due to their hydrophobic and oleophobic properties and stability.

TranSpreadJun 24 2024 Polyfluoroalkyl substances are a class of chemicals extensively used in consumer goods production due to their hydrophobic and oleophobic properties and stability. However, their persistence in the environment and bioaccumulation in living organisms have sparked concerns about potential health effects. Previous studies have linked PFAS exposure to various adverse outcomes, including developmental issues in children.

A recent study published in Eco-Environment & Health on May 8, 2024, has highlighted the levels, health risks, and transport protein binding capabilities of per- and polyfluoroalkyl substances in early life based on the Shanghai Maternal-Child Pairs Cohort. Found in maternal serum, cord serum, and breast milk, these synthetic chemicals pose potential health risks for infants.

Employing high-performance liquid chromatography-tandem mass spectrometry, the study analyzed 16 types of PFAS in 1,076 mother-child pairs. It revealed the detection rates and median concentrations of perfluorooctane sulfonate , perfluorooctanoic acid , and 6:2 Cl-PFESA, with PFOS most prevalent in maternal serum.

Our findings are crucial for developing strategies to protect infants from the potentially harmful effects of PFAS exposure. Understanding the pathways and risks associated with these chemicals can lead to better regulatory policies and protective measures for the most susceptible among us." The implications of this research are profound, particularly for public health policies and infant safety.

 

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